BUFFALO, N.Y. — A groundbreaking treatment is reshaping the lives of many Americans grappling with obesity and diabetes. With a simple weekly injection, GLP-1 medications are proving to be a game-changer in weight management and blood sugar control.
Abraham Markez, once struggling with severe obesity at 490 pounds, is now a testament to the success of GLP-1 medications. In just 18 months, Markez has shed nearly 300 pounds, bringing his weight down to a healthy 191 pounds. His remarkable transformation was facilitated by Mounjaro, a GLP-1 medication that not only aids in blood sugar regulation but also promotes significant weight loss. This medication works by slowing digestion, enhancing feelings of fullness, and reducing cravings, which some experts attribute to its effect on satiety signals in the brain.
“Food noise,” as Markez describes it—distractions and cravings from fast food and other temptations—diminished significantly once he started the medication. “It affects more than just food. It helps people make healthier choices overall, such as quitting smoking or avoiding gambling and alcohol,” he explained.
Mounjaro, similar to Ozempic, is administered as a once-weekly injection and has been pivotal in managing diabetes. The drug’s side effect of weight loss has been a notable benefit. According to manufacturers, users typically experience up to a 20% reduction in total body weight. The medication’s impact extends beyond weight loss; it also significantly lowers the risk of cardiovascular events, as highlighted by Dr. Howard Lippes, an endocrinologist at R&B Medical Group.
Dr. Lippes emphasizes the critical role of these medications in reducing cardiovascular risks, particularly among individuals with type 2 diabetes and obesity. “The leading causes of death in America—stroke and heart attack—are exacerbated by obesity and diabetes. These medications have shown a remarkable ability to mitigate those risks,” he said.
The GLP-1 drugs, while highly effective, are not a cure-all. Dr. Lippes points out that they are designed to be used in conjunction with lifestyle changes. “These medications have been around for decades and are highly effective in treating insulin resistance and fatty liver disease. However, they are most beneficial when combined with healthy lifestyle practices.”
Moreover, addressing obesity can have far-reaching benefits beyond cardiovascular health. Dr. Lippes notes that reducing excess body fat can lead to a significant decrease in obesity-related cancers, including liver cancer. “Many cancers are linked to obesity, and we anticipate that reducing fat will lower the incidence of these cancers.”
Despite their effectiveness, GLP-1 medications are not a “magic shot.” Markez underscores the importance of complementary lifestyle adjustments. “The medicine helps, but it’s not a cure-all. You have to work with it—eat healthily, stay hydrated, and manage stress. The medication supports your efforts, but you need to put in the work,” he advises.
Markez’s journey illustrates that while GLP-1 medications offer significant health improvements, achieving optimal results requires a commitment to a healthier lifestyle alongside the medication. “It’s not a miracle drug, but it’s a remarkable advancement in treatment. This medication has made a huge difference in my life, and it’s an exciting time for those of us battling obesity and diabetes,” he concluded.
