What’s up with obesity? What is the cause?
Etiological classification
It is divided into two categories: simple obesity and secondary obesity.
(1) Simple obesity
No obvious cause of endocrine or metabolic disease can be found.
- Constitutional obesity, also known as juvenile-onset obesity.
- Acquired obesity, also known as adult-onset obesity.
(2) Secondary obesity
There are obvious etiologies such as endocrine and metabolic diseases that can be investigated.
- Hypothalamic disease
(1) Hypothalamic syndrome: Various causes such as inflammatory sequelae, trauma, tumor, granuloma, etc. can lead to hypothalamic syndrome obesity.
(2) Obese reproductive infertility: also known as Frohlich syndrome.
- Pituitary disease
(1) Pituitary ACTH cell tumor: also known as Cushing’s disease.
(2) Pituitary growth hormone (GH) cell tumor: also known as acromegaly.
(3) Pituitary prolactin (PRL) cell tumor
- Hypothyroidism
(1) Primary (thyroid) hypothyroidism.
(2) Hypothalamic-pituitary hypothyroidism.
- Insulin disease
(1) Early stage of non-insulin-dependent (NIDDM, type 2) diabetes.
(2) Insulinoma: also known as pancreatic islet B-cell tumor.
(3) Functional spontaneous hypoglycemia.
- Hyperadrenocorticism Also known as hypercortisolism, Cushing’s syndrome.
- Hypogonadism
(1) Menopausal obesity in women.
(2) Polycystic ovary syndrome.
(3) Male anorchidism or anorchidism.
- Others
(1) Obesity pain (Dercum disease).
(2) Water and sodium retention obesity.
(3) intracranial plate hyperplasia (Morgagni-Stewart-Morel syndrome).
(4) Infantile-retinitis pigmentosa-polydactyly (toe) deformity syndrome (Laurence-Moon-Biedl syndrome).
- Drug-induced obesity The long-term use of chlorpromazine in mentally ill patients, the long-term use of insulin in some diseases, the promotion of protein synthesis preparations, glucocorticoids, and assimil can make the patients hyper-appetite and lead to obesity.
