The term “budget Ozempic” has been making waves across social media platforms, piquing the curiosity of those seeking a weight loss solution. These so-called “budget Ozempic” drugs, often recognized as laxatives and stool softeners, are gaining popularity for their perceived weight loss effects. However, this growing demand, particularly in the United States, has raised concerns of potential shortages in pharmacies.
These laxatives represent the latest in a series of alternatives endorsed by influencers as substitutes for the blockbuster drug Ozempic. But what exactly is “budget Ozempic,” and does it truly aid in weight loss? It’s crucial to understand that any weight loss achieved through these laxatives is likely to be temporary, and long-term use may pose health risks.
Ozempic in High Demand
Ozempic contains semaglutide as its active ingredient and is a prescription-only medication primarily prescribed for the treatment of type 2 diabetes. One of its notable side effects is significant weight loss, resulting in an increased demand for the drug and subsequent shortages in the market.
In response to these shortages, some individuals have turned to readily available over-the-counter alternatives in their pursuit of weight loss. Among these alternatives is berberine, often referred to as “nature’s own Ozempic.”
Understanding ‘Budget Ozempic’
“Budget Ozempic” distinguishes itself from “nature’s own Ozempic.” It is comprised of the polymer polyethylene glycol 3350, or PEG 3350 for short. Chemically akin to other polymers used in cosmetics, drug delivery systems, archaeological preservation, soaps, and even missile fuel, PEG 3350 is not to be confused with ethylene glycol, which is employed in antifreeze.
Medically, PEG 3350 is primarily available in Australia through pharmacies as an ingredient in laxatives and stool softeners. It is also used for bowel cleansing prior to a colonoscopy and is commonly referred to as a macrogol, found in products such as DulcoSoft, Movicol, OsmoLax, ClearLax, and ColonLYTELY.
Mechanism of Weight Loss
PEG 3350 is categorized as an osmotic laxative. It operates through osmosis, affecting the balance of electrolytes in the blood serum to soften stools and alleviate constipation. When PEG 3350 is ingested, it does not get absorbed by the body. Instead, it draws water into the intestines as it passes through, leading to a more watery consistency in feces.
However, any weight loss experienced due to PEG 3350 is transient, primarily because it induces dehydration. The lost weight is largely attributed to water loss, and the body tends to retain water upon subsequent fluid intake. To achieve significant and sustained weight loss, a substantial daily intake of PEG 3350 would be required, resulting in only modest reductions in weight.
This differs from the mode of action of Ozempic, which mimics a family of hormones in the body known as incretins, impacting blood sugar levels and appetite regulation. Ozempic helps with sustained weight loss by slowing food absorption from the stomach and reducing appetite.
Potential Dangers and Side Effects
The use of PEG 3350 may lead to dehydration, manifesting in symptoms such as dizziness, lightheadedness, headaches, dry mouth, lips, or eyes. It can also cause hypertonic blood serum, affecting red blood cells’ shape and oxygen-carrying capacity, resulting in fatigue and other dehydration symptoms.
Incorrect electrolyte levels can have serious consequences, impacting the heart, muscles, and potentially leading to seizures, confusion, and coma. Individuals with heart disease, those on sodium-restricted diets, or those with existing electrolyte disorders should exercise caution with PEG 3350. It can also pose risks to elderly individuals, those with kidney problems, and young children.
Common side effects may include anal irritation, vomiting, diarrhea, nausea, cramps, abdominal pain, and swelling. Some individuals may experience allergic reactions. Prolonged use of PEG 3350-based products can lead to withdrawal symptoms when discontinued, including constipation, bloating, weight gain, and fluid retention.
In Summary
For those seeking effective and safe weight loss solutions, PEG 3350-based products, colloquially referred to as “budget Ozempic,” are not recommended. Any weight loss achieved is likely to be temporary and may endanger one’s health. It is advisable to consider healthier eating habits and regular exercise as the initial steps toward weight management. For more comprehensive assistance with weight loss, individuals are encouraged to consult with their healthcare providers or pharmacists who can provide guidance on lifestyle changes and appropriate medication options.
