Obesity mainly comes from eating more. People who eat more often have a good appetite. Suppressing appetite, reducing food intake, and reducing the absorption and utilization of food are the purpose of Western medicine to lose weight. The following are some of the commonly used drugs:
(1) Amphetamines: also known as appetite agents. Its main pharmacological effect is to affect the satiety center of the hypothalamus through the excitatory effect on the center, so that the patient’s appetite decreases. The drug also causes increased central nervous system excitability, decreased sleep, and increased consumption, resulting in weight loss. The side effects include insomnia, nervousness and palpitation and other sympathetic nervous excitement, and long-term use can be addictive. Patients with hypertension, coronary heart disease, hyperthyroidism and obesity diabetes should not use this drug. In order to promote strengths and avoid weaknesses, a variety of amphetamine drugs have been prepared, among which fenfluramine (trifluoromethyl m-phenethylamine) has the best effect. In addition to suppressing appetite, the drug also promotes the uptake of glucose by muscle cells, reducing the conversion of glucose to fat, and the side effects of sympathetic nerve stimulation are not obvious. , Diabetes, coronary heart disease, hypertension patients can take, the general dosage is 20 mg, 3 times a day. my country can produce.
(2) Biguanide hypoglycemic drugs: by increasing the meta-oxygen glycosidase in the tissue, promoting the uptake of glucose by the tissue, reducing blood sugar and hyperinsulinemia; using the gastrointestinal reaction of the drug, reducing appetite, and also inhibiting the intestinal tract absorption of glucose. Side effects include fatigue, severe gastrointestinal reactions such as nausea, vomiting and diarrhea, and lactic acidosis may be caused by excessive production of lactic acid. Commonly used oral tablets include Jiangtangling (Phenyldimus) 25 mg, 3 times a day; Jiangtang Tablets (Metformin), 0.25 g, 3 times a day.
(3) α-glucosidase inhibitor: The absorption of carbohydrates in the intestinal tract depends on the help of the small glucosidase secreted by the small intestinal mucosal cells, inhibiting the effect of the small glucosidase, that is, it can reduce the absorption of carbohydrates in the intestinal tract . At present, several glucosidase inhibitors have been developed, and the most studied is acarbose (produced by Bayer, Germany). Its safety and effectiveness have been affirmed by clinical studies, and the usual dose is 50-100 mg, 2-3 times a day. Another miglitol (same from Bayer company), similar to the clinical effect of acarbose, the therapeutic dose is 50-100 mg, 3 times a day. These drugs are all taken with meals, and the side effects are carbohydrate malabsorption, abdominal distension and diarrhea. The occurrence of side effects is positive with the size of the medication, so the medication should be taken in moderation. The drug has not yet been put on the domestic market.
(4) Hormonal drugs, thyroid hormone-thyroid tablets (80-160 mg/day), triiodothyronine (T3, 50 micrograms/day), reduce body weight by improving energy metabolism and increasing calorie consumption, taking The amount needs to exceed the physiological needs, so it can cause tachycardia. It is necessary to take propranolol (10 mg, 2-3 times / day) at the same time to slow down the heart rate.
Indications and precautions of Western medicine for weight loss
- Western medicine for weight loss is only suitable for moderately and severely obese patients.
- Since the drugs described above have certain side effects, they must be taken under the guidance of a doctor.
- The side effects of drugs are often positive Lh with the dosage, that is, the greater the dosage, the greater the side effects. In addition, each person’s sensitivity to the drug has its individual differences, so it is necessary to start with a small dose and gradually increase to an effective dose.
- Changes in body weight and relevant biochemical indicators in the blood, such as blood sugar and blood lipids, should be monitored before and during the drug administration to observe the curative effect and help to adjust the dosage of the drug.
- Those who take a large amount of medicine should not discontinue the medicine suddenly, and gradually stop the medicine under the guidance of the doctor.
Tips: For more information on: drug weight loss, bariatric surgery, liposuction to lose weight, please pay attention to: gtehy.com, which provides you with comprehensive and professional weight loss plan for men, vegetarian weight loss plan, weight loss supplements and so on.
