(NewsNation) — The question once posed by Dr. Oz on his show—whether a diabetes drug could combat obesity—has received a significant endorsement from recent research. The medication in question, semaglutide, marketed as Ozempic and Wegovy, has been shown to be effective for long-term weight management, according to a new study.
Study Findings
Recent research from the Cleveland Clinic has demonstrated that semaglutide, a prescription-only injectable drug, significantly supports long-term weight loss in patients with obesity. This study evaluated key factors that influence the medication’s effectiveness.
Among the participants—more than 3,400 individuals with obesity, over half of whom were female—the study revealed that those on higher doses of semaglutide achieved greater weight loss. Furthermore, patients who adhered to the medication for over 90 days experienced better results compared to those who took it for shorter periods. Notably, women showed a higher success rate in weight reduction after one year compared to men.
Mechanism of Action
“Ozempic operates by targeting GLP-1 receptors in the brain, which are responsible for regulating appetite and blood sugar levels,” explained Marlee Bruno, a certified physician’s assistant and founder of Mind Body & Soul Medical in Pensacola, Florida. “It’s crucial, however, to recognize that Ozempic is not a standalone solution. It should be used as part of a broader lifestyle modification plan, including dietary adjustments, regular exercise, and avoiding processed foods.”
Popularity and Demand
Since its FDA approval in 2017 for Type 2 diabetes, Ozempic has gained widespread attention for its weight loss benefits. The medication’s popularity surged, partly due to social media trends like the #OzempicChallenge and endorsements from influencers. This increased demand led to a reported shortage, as acknowledged by the FDA.
Sustained Benefits
Research underscores the importance of sustained weight loss, noting that reductions of 10% or more can yield significant health improvements. Despite initial skepticism about the drug’s effectiveness, the current evidence supports Ozempic as a serious, scientifically validated treatment for obesity.
Wegovy and Supply Issues
Wegovy, a higher-dose variant of semaglutide, is also experiencing limited availability due to high demand. The FDA’s shortage declaration, which began in August 2022, continues to impact supply.
Potential Risks
As with any medication, there are potential risks associated with semaglutide. The FDA has issued warnings about the risks of overdose, and other studies suggest that rapid weight loss may impact bone density, particularly in individuals over 65 or those with osteoporosis. “It’s vital to use Ozempic under medical supervision, ensuring that dosage is adjusted as needed and progress is carefully monitored,” Bruno advised.
Conclusion
The study reaffirms that Ozempic is a powerful tool in the fight against obesity, offering long-term weight loss benefits when used responsibly alongside lifestyle changes. Its effectiveness and growing recognition reflect its significant role in modern weight management strategies.
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