Veterinary toxicologists are issuing warnings regarding the potential dangers of accidental exposure to semaglutide-based weight loss medications, such as Ozempic, after several cases where pet owners mistakenly administered the drug to their diabetic pets.
Since the introduction of semaglutide-based medications like Ozempic, Pet Poison Helpline has responded to numerous reports where clients accidentally gave their pets these weight loss drugs instead of their prescribed insulin. As a result, Pet Poison Helpline is urging pet owners to be cautious and aware of the risks these medications pose to animals.
“If you’re not paying close attention, it’s easy to confuse Ozempic with insulin,” explained Dr. Renee Schmid, DVM, DABT, DABVT, a senior veterinary toxicologist and director of Veterinary Medicine at Pet Poison Helpline. “Although some insulin for pets is administered with an autoinjector pen, most are given with insulin syringes. However, the growing popularity of weight-loss medications like Ozempic has led to increased familiarity with the new autoinjector pens. These medications are often stored together in the refrigerator, increasing the risk of mix-ups with potentially harmful consequences.”
According to Pet Poison Helpline, nearly 50% of calls involve human medications—both over-the-counter and prescription. The most common medications involved in poisoning cases include:
- NSAIDs
- Acetaminophen
- Antidepressants
- ADD/ADHD medications
- Benzodiazepines and sleep aids
- Birth control
- ACE Inhibitors
- Beta-blockers
- Thyroid hormones
- Cholesterol-lowering agents
In one case highlighted by Pet Poison Helpline, a Siberian husky from Oregon accidentally received multiple doses of Ozempic instead of insulin. The dog became lethargic and vomited upon the return of its owner, who rushed the pet to the hospital. After treatment for hypoglycemia, it was discovered that the pet had mistakenly been administered Ozempic. The husky was kept in the hospital for two days for supportive care and eventually made a full recovery.
A similar incident occurred with a cat named Mario, who was under the care of a family member. When Mario’s owner returned, the cat was found “nearly comatose,” and it was revealed that at least one dose of Ozempic had been given instead of insulin. Mario was treated for severe hypoglycemia and dehydration, requiring dextrose, IV fluids, and intensive care.
“Leaving your pet in the care of someone unfamiliar with their routine can be stressful,” said Dr. Schmid. “If you plan to have someone else care for your pet, it’s essential to thoroughly review their medication regimen, including any special instructions for food or treats. To minimize risk, medications should be kept out of sight to avoid confusion.”
In addition to accidental injections, Schmid warns that pets may ingest Ozempic if they find and chew on medication pens. To prevent such incidents, she advises pet owners to store medications separately from their pets’ prescriptions and ensure all medications are kept in places where pets and young children cannot access them.
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