A recent study has raised concerns about the potential side effects of Ozempic, a popular drug used for diabetes management and weight loss, revealing that it may more than double the risk of developing a rare, yet serious condition that can lead to blindness.
Ozempic, often hailed as a “miracle” weight-loss drug, has gained global attention for its effectiveness in helping individuals shed pounds. However, two major studies conducted by the University of Southern Denmark have uncovered a troubling connection between the drug and non-arteritic anterior ischemic optic neuropathy (NAION), a condition that disrupts blood flow to the optic nerve and can result in permanent vision loss.
The first study, which tracked 424,152 diabetic patients over five years, found that the incidence of NAION rose from 9 to 23 cases per 100,000 among those using Ozempic. Published in the International Journal of Retina and Vitreous, the study highlights the irreversible nature of NAION and stresses the importance of vigilance regarding this potential risk.
In a second study involving 62,000 participants from Denmark and Norway, the incidence of NAION increased to 21 per 100,000 individuals using Ozempic. These findings have prompted health experts to advise monitoring patients using the drug for early signs of the condition.
Dr. Paul Ian Cross, a health expert contributing to MedicalNewsToday, emphasized that while the risk of NAION should not be overlooked, the studies do not suggest discontinuing Ozempic for diabetic patients. Instead, patients are encouraged to be vigilant and seek regular eye check-ups. While untreated diabetes can lead to eye complications, those associated with NAION tend to be more severe.
Since its approval for diabetes management in South Africa in 2017, Ozempic has also gained popularity as a weight-loss solution. It works by mimicking a natural hormone that signals the brain to reduce appetite and slows digestion, making it effective for both weight loss and blood sugar control. The drug, originally developed for long-term use, often results in weight loss as a side effect for diabetic patients.
However, experts, including Dr. Marius Wasserfall, an internist at Mediclinic, have also cautioned about rare but serious side effects, including inflammation of the pancreas and gallbladder issues. Additionally, Dr. Wasserfall warned that some individuals may regain much of the weight lost once they stop using Ozempic.
As more people turn to Ozempic for weight loss, health professionals urge caution and suggest patients regularly monitor their eye health while undergoing treatment.
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