The dramatic weight loss effects of so-called “miracle” drugs like Ozempic have sparked global interest — but they may come with a visible downside.
Dr. Judey Pretorius, founder of Biomedical Emporium, joined broadcaster Aubrey Masango to discuss a growing concern among users of GLP-1 medications: a side effect now widely referred to as “Ozempic face.”
Medications such as Ozempic, Wegovy, Saxenda, and Mounjaro — all part of the GLP-1 drug category — have become popular for their ability to trigger rapid weight loss. Several celebrities have credited these drugs for their striking physical transformations.
While the results are often remarkable, the side effects are becoming increasingly noticeable. One in particular has caught public attention.
“Ozempic face” describes the hollowed, aged appearance some users develop after rapid weight loss. Patients report sagging skin, more pronounced wrinkles, and a general thinning of the face, giving it a prematurely aged look.
According to Dr. Pretorius, users can lose between 15% to 20% of their body weight within six months. For younger patients, the skin tends to adjust well. However, those over the age of 35 may struggle with the effects of such rapid changes.
The speed and extent of weight loss, she explains, can lead to a loss of facial fat and elasticity in older users — resulting in the noticeable condition now dubbed “Ozempic face.”
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