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What’s up with obesity? What is the cause?

Etiological classification

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It is divided into two categories: simple obesity and secondary obesity.

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(1) Simple obesity

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No obvious cause of endocrine or metabolic disease can be found.

  1. Constitutional obesity, also known as juvenile-onset obesity.
  2. Acquired obesity, also known as adult-onset obesity.

(2) Secondary obesity

There are obvious etiologies such as endocrine and metabolic diseases that can be investigated.

  1. Hypothalamic disease

(1) Hypothalamic syndrome: Various causes such as inflammatory sequelae, trauma, tumor, granuloma, etc. can lead to hypothalamic syndrome obesity.

(2) Obese reproductive infertility: also known as Frohlich syndrome.

  1. Pituitary disease

(1) Pituitary ACTH cell tumor: also known as Cushing’s disease.

(2) Pituitary growth hormone (GH) cell tumor: also known as acromegaly.

(3) Pituitary prolactin (PRL) cell tumor

  1. Hypothyroidism

(1) Primary (thyroid) hypothyroidism.

(2) Hypothalamic-pituitary hypothyroidism.

  1. Insulin disease

(1) Early stage of non-insulin-dependent (NIDDM, type 2) diabetes.

(2) Insulinoma: also known as pancreatic islet B-cell tumor.

(3) Functional spontaneous hypoglycemia.

  1. Hyperadrenocorticism Also known as hypercortisolism, Cushing’s syndrome.
  2. Hypogonadism

(1) Menopausal obesity in women.

(2) Polycystic ovary syndrome.

(3) Male anorchidism or anorchidism.

  1. Others

(1) Obesity pain (Dercum disease).

(2) Water and sodium retention obesity.

(3) intracranial plate hyperplasia (Morgagni-Stewart-Morel syndrome).

(4) Infantile-retinitis pigmentosa-polydactyly (toe) deformity syndrome (Laurence-Moon-Biedl syndrome).

  1. Drug-induced obesity The long-term use of chlorpromazine in mentally ill patients, the long-term use of insulin in some diseases, the promotion of protein synthesis preparations, glucocorticoids, and assimil can make the patients hyper-appetite and lead to obesity.

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