What is Sibutramine?
Sibutramine, a monoamine reuptake inhibitor that acts on the central nervous system, increases the amount of neurotransmitters and reduces appetite in the user. In 1997, sibutramine was approved by the U.S. Food and Drug Administration to launch the market, used in combination with low-calorie foods to lose weight and maintain weight, for people with an initial body mass index (BMI) greater than 30, or BMI greater than or equal to 27, but there are People with other risk factors (eg, high blood pressure, diabetes).
However, due to the increased risk of heart disease, countries such as the United States, Europe, the European Union, and Taiwan have successively revoked the drug’s license and ordered drug manufacturers to recall it. On October 30, 2010, China announced the cessation of production, sales and use of sibutramine, revoked its approval documents, and recalled and destroyed the drugs already on the market.
So, how to choose diet pills?
There are now a wide variety of weight loss drugs, including appetite control drugs, gastrointestinal lipase inhibitors, and defecation-promoting drugs. There are currently 6 drugs approved by the US FDA, including phentermine, orlistat, phentermine/topiramate delayed-release, lorcaserin, naltrexone/bupropion delayed-release and liraru peptides.
However, as the saying goes, medicine is poisonous, and any medicine has its side effects. For example, orlistat, which is currently the only weight loss drug approved in my country, is a selective gastrointestinal lipase inhibitor, which can inhibit the absorption of about 30% of dietary fat and reduce cholesterol content, thereby reducing body weight. But orlistat may cause gastrointestinal discomfort, which can easily lead to intestinal disorders, which can be manifested as abdominal pain, diarrhea, constipation, nausea, etc. In addition, there is a very embarrassing side effect, which is called on the Internet, “If you eat oreslitate, your butt may flow oil”, which means that the oil that is not absorbed will flow out from the chrysanthemum part involuntarily.
In addition, with drugs that promote defecation, the body will be in a state of diarrhea for a long time, which will lead to electrolyte imbalance in the body, and even lead to shock in severe cases. Appetite control drugs are used to stimulate the satiety center to make people feel world-weary, reduce appetite, and achieve the purpose of diet control. However, such drugs may cause myocardial infarction, and severe hallucinations and auditory hallucinations may occur.
Do you really need to lose weight?
At present, the most commonly used international standard to measure health is body mass index (BMI), which was first proposed by the Belgian generalist Kettler in the mid-19th century. The calculation formula is: body mass index (BMI) = weight (kg) / height (m)^2 .
After excluding some athletes, fitness enthusiasts, and pregnant women, for adults, a BMI greater than 30 is obese, a BMI between 25 and 30 is overweight, and a BMI between 18.5 and 25 is normal weight. . Therefore, a BMI greater than 25 needs to be “slim down”!
Although obesity is related to genes, fat genes do not completely determine your body shape. The factors that really determine whether you are fat or thin are mainly related to living habits, eating habits, and exercise habits! The British Medical Journal published a research report that analyzed nearly 9,000 people and found that as long as they adhere to scientific methods, people who carry the fat gene can also have a good body.
The World Health Organization (WHO) emphasizes:
- Healthy diet: limit intake from total fat and shift fat intake from saturated to unsaturated fat; use more fruits, vegetables, legumes, whole grains and nuts; limit free sugar and salt intake.
- Moderate exercise: Regularly doing at least 150 minutes of moderate-intensity exercise every week can reduce the risk of cardiovascular disease, diabetes, colon cancer and breast cancer; strengthening muscles and exercising balance can reduce the risk of falls in middle-aged and elderly people. Improve their mobility; if you want to lose weight, you need to increase the amount of exercise.
To sum up, there are thousands of ways to control weight, and in the final analysis, it is still a “healthy lifestyle”. If you really want to lose weight, there is really no shortcut. The Great Wall is not built in a day, and weight is not gained in a day. Eat a healthy diet, exercise reasonably, go to bed early and get up early, maintain a healthy routine and life pattern, stick to it, you will lose weight!
